Segmenting Brain Tumors from MRI Using Cascaded 3D U-Nets

In this paper, we exploit a cascaded 3D U-Net architecture to perform detection and segmentation of brain tumors (low- and high-grade gliomas) from multi-modal magnetic resonance scans. First, we detect tumors in a binary-classification setting, and they later undergo multi-class segmentation. To provide high-quality generalization, we investigate several regularization techniques that help improve the segmentation performance obtained for the unseen scans, and benefit from the expert knowledge of a senior radiologist captured in a form of several post-processing routines. Our preliminary experiments elaborated over the BraTS’20 validation set revealed that our approach delivers high-quality tumor delineation.